Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758814 | 0.81 | HDAC1 (0.45) | MAPK1KDM4EL3MBTL1POLBNPC1 | |
| SCHEMBL12488583 | 0.79 | MAPK1 (0.67) | MAPK1KDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL27076571 | 0.78 | MAPK1 (0.38) | MAPK1MGLLKDM4EL3MBTL1NPC1 | |
| SCHEMBL16938414 | 0.78 | GABRP (0.49) | MAPK1MGLLKDM4EL3MBTL1NPC1 | |
| SCHEMBL12727641 | 0.78 | POLB (0.49) | MGLLL3MBTL1POLBNPC1RAB9A | |
| SCHEMBL1509187 | 0.77 | MAPK1 (0.41) | MAPK1MGLLKDM4EL3MBTL1HCAR3 | |
| SCHEMBL300884 | 0.77 | CA12 (0.42) | MAPK1MGLLKDM4ERAB9AKMT2A | |
| SCHEMBL30914672 | 0.76 | MAPK1 (0.40) | MAPK1MGLLKDM4EL3MBTL1HCAR3 | |
| SCHEMBL1445644 | 0.76 | MAPK1 (0.40) | MAPK1MGLLKDM4EL3MBTL1HCAR3 | |
| Hydrochloric Acid SCHEMBL5087052 | 0.76 | MAPK1 (0.40) | MAPK1MGLLKDM4EL3MBTL1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771646-B2 | Nicotinic acid and picolinic acid derived near-infrared fluorophores | VISEN MEDICAL, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130272967-A1 | Nicotinic Acid and Picolinic Acid Derived Near-Infrared Fluorophores | VISEN MEDICAL, INC. | 2013-10-17 | — | — | US | disclosed |
| US-8455651-B2 | Nicotinic acid and picolinic acid derived near-infrared fluorophores | VISEN MEDICAL, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-8173819-B2 | Nicotinic and picolinic acid derived near-infrared fluorophores | VISEN MEDICAL, INC. (US) | 2012-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130272967-A1 | Nicotinic Acid and Picolinic Acid Derived Near-Infrared Fluorophores | NAPRT, NAMPT, HCAR2 | MAPK1 2187/4885MGLL 4568/4885KDM4E 4807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.