Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.56 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | AGXT | P21549 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924069 | 0.83 | CALM1 (0.52) | CALM1CAMKK2AOC3TAAR1IDO1 | |
| SCHEMBL29547354 | 0.80 | CALM1 (0.64) | CALM1CAMKK2AOC3TAAR1IDO1 | |
| SCHEMBL850832 | 0.80 | CALM1 (0.64) | CALM1CAMKK2AOC3TAAR1IDO1 | |
| SCHEMBL1134084 | 0.80 | KMT2A (0.61) | CALM1CAMKK2AOC3TAAR1IDO1 | |
| SCHEMBL4739963 | 0.79 | PYCR1 (0.64) | AOC3TAAR1IDO1AGXTKMT2A | |
| SCHEMBL30093216 | 0.77 | CALM1 (0.60) | CALM1CAMKK2AOC3TAAR1IDO1 | |
| SCHEMBL14492586 | 0.77 | AOC3 (0.70) | CALM1CAMKK2AOC3TAAR1IDO1 | |
| SCHEMBL4526554 | 0.76 | CALM1 (0.55) | CALM1CAMKK2AOC3TAAR1IDO1 | |
| SCHEMBL6461595 | 0.75 | TAAR1 (0.55) | AOC3TAAR1IDO1AGXTCHRM2 | |
| SCHEMBL14920640 | 0.75 | TAAR1 (0.55) | CALM1CAMKK2AOC3TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417190-B1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-10-22 | — | — | EP | claimed |
| EP-1416933-B1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM INC (US) | 2008-01-02 | — | — | EP | claimed |