Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786270 | 0.91 | KMT2A (0.60) | APLNRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26324037 | 0.81 | APLNR (0.65) | APLNRALDH1A1PKMTAS1R3TAS1R1 | |
| SCHEMBL2226834 | 0.80 | APLNR (0.63) | APLNRALDH1A1PKMTAS1R3TAS1R1 | |
| SCHEMBL20496920 | 0.78 | APLNR (0.61) | APLNRALDH1A1PKMTAS1R3TAS1R1 | |
| SCHEMBL18415441 | 0.76 | TAS1R3 (0.67) | APLNRALDH1A1PKMMEN1KMT2A | |
| SCHEMBL10643468 | 0.76 | APLNR (0.67) | APLNRALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8829977 | 0.75 | TAS1R3 (0.68) | APLNRALDH1A1MEN1KMT2ATAS1R3 | |
| SCHEMBL933063 | 0.75 | APLNR (0.76) | APLNRALDH1A1PKMMEN1KMT2A | |
| SCHEMBL10141758 | 0.75 | APLNR (0.65) | APLNRALDH1A1PKMTAS1R3TAS1R1 | |
| SCHEMBL2261220 | 0.75 | APLNR (0.65) | APLNRALDH1A1PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077170-A2 | BENZOTHIOAMIDES, AND USE THEREOF FOR RELAXING SMOOTH MUSCLES | Universität Wien (AT) | 2008-07-03 | — | — | WO | disclosed |