Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.68 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701170 | 0.81 | TAS1R3 (1.00) | TAS1R3TAS1R1HPGDNPSR1POLB | |
| SCHEMBL22501325 | 0.80 | TAS1R3 (0.71) | TAS1R3TAS1R1HPGDNPSR1POLB | |
| SCHEMBL14817128 | 0.78 | TAS1R3 (0.76) | TAS1R3TAS1R1HPGDNPSR1POLB | |
| SCHEMBL4739573 | 0.75 | APLNR (0.56) | TAS1R3TAS1R1NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8829967 | 0.75 | TAS1R3 (0.67) | TAS1R3TAS1R1HPGDNPSR1POLB | |
| SCHEMBL31016553 | 0.75 | TAS1R3 (0.64) | TAS1R3TAS1R1HPGDNPSR1POLB | |
| SCHEMBL13693769 | 0.74 | KMT2A (0.62) | NPSR1POLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL26324037 | 0.73 | APLNR (0.65) | TAS1R3TAS1R1HPGDNPSR1POLB | |
| SCHEMBL4786270 | 0.72 | KMT2A (0.60) | POLBALDH1A1SMN1; SMN2APLNRMAPT | |
| SCHEMBL2226834 | 0.72 | APLNR (0.63) | TAS1R3TAS1R1HPGDNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616711-A | REACTING BUTENE DERIVATIVE TO AN AMIDE DERIVATIVE; USEFUL AS INTERMEDIATES FOR PRODUCING ANTIULCER DRUGS | FUJIREBIO INC. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0582304-A2 | Methods of producing amino butene derivatives | FUJIREBIO Inc. (JP) | 1994-02-09 | — | — | EP | disclosed |