Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737107 | 0.88 | GAA (0.58) | GAATSHRPDK1HTTCYP3A4 | |
| SCHEMBL4737668 | 0.80 | GAA (0.56) | GAATSHRPDK1MLYCDHTT | |
| SCHEMBL4737949 | 0.77 | GAA (0.52) | GAATSHRPDK1MLYCDHTT | |
| SCHEMBL5260135 | 0.77 | TSHR (0.44) | GAATSHRPDK1HTTHDAC6 | |
| SCHEMBL4786167 | 0.76 | GAA (0.51) | GAATSHRPDK1MLYCDHTT | |
| SCHEMBL4738782 | 0.76 | MAPK14 (0.45) | GAATSHRPDK1HDAC6HDAC8 | |
| SCHEMBL4738966 | 0.74 | GAA (0.54) | GAATSHRPDK1MLYCDHTT | |
| SCHEMBL4737592 | 0.74 | GAA (0.56) | GAATSHRPDK1HTTCYP3A4 | |
| SCHEMBL4738735 | 0.73 | AGER (0.49) | GAATSHR | |
| SCHEMBL4738946 | 0.73 | ALDH1A1 (0.43) | GAATSHRPDK1HTTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |