Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13904218 | 0.74 | — | — | |
| SCHEMBL7837272 | 0.74 | — | — | |
| SCHEMBL10094591 | 0.74 | — | — | |
| SCHEMBL25155579 | 0.73 | MCL1 (0.42) | MCL1DAOAURKAAURKBINCENP | |
| SCHEMBL11463688 | 0.71 | L3MBTL1 (0.37) | ALDH1A1HSD17B10KDM4EGAAL3MBTL1 | |
| SCHEMBL969786 | 0.71 | — | — | |
| SCHEMBL5638899 | 0.71 | MCL1 (0.44) | MCL1DAOAURKAAURKBINCENP | |
| SCHEMBL10094130 | 0.71 | BLM (0.45) | MCL1DAOAURKAAURKBINCENP | |
| SCHEMBL16794593 | 0.69 | NAPRT (0.52) | DAOAURKAAURKBINCENPBLM | |
| SCHEMBL20033714 | 0.69 | BLM (0.44) | MCL1DAOAURKAAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101668744-A | Process for producing 1-substituted-2-pyridone-3-carboxylic acid derivative | SHIONOGI & CO | 2010-03-10 | — | — | CN | disclosed |
| CN-101668744-A | Process for producing 1-substituted-2-pyridone-3-carboxylic acid derivative | SHIONOGI & CO | 2010-03-10 | — | — | CN | disclosed |
| WO-2008084671-A1 | PROCESS FOR PRODUCING 1-SUBSTITUTED-2-PYRIDONE-3-CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2008-07-17 | — | — | WO | disclosed |
| US-7220856-B2 | Substituted quinoline CCR5 receptor antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-05-22 | — | — | US | disclosed |
| CN-1678586-A | Substituted quinoline CCR5 receptor antagonists | SCHERING AG (DE) | 2005-10-05 | — | — | CN | disclosed |
| US-20040072818-A1 | Substituted quinoline CCR5 receptor antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072818-A1 | Substituted quinoline CCR5 receptor antagonists | CCR5, CXCR3, CCR2 | MCL1 1088/4885DAO 4130/4885AURKA 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.