Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054038 | 0.85 | AURKA (0.54) | GBA1AOC3MEN1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL4782322 | 0.84 | AURKA (0.53) | GBA1AOC3MEN1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3058359 | 0.84 | AURKA (0.53) | GBA1AOC3MEN1CYP1A2CYP3A4 | |
| SCHEMBL4739795 | 0.76 | HDAC3 (0.51) | AOC3HDAC1MAPK1 | |
| SCHEMBL3844597 | 0.76 | LTA4H (0.59) | LTA4HMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15275960 | 0.75 | GBA1 (0.43) | GBA1AOC3KMT2AKDM4EMAPT | |
| SCHEMBL30175373 | 0.75 | GBA1 (0.60) | GBA1AOC3CYP1A2KDM4EL3MBTL1 | |
| SCHEMBL8430068 | 0.75 | GBA1 (0.60) | GBA1AOC3CYP1A2KDM4EL3MBTL1 | |
| SCHEMBL13090580 | 0.72 | KDM4E (0.72) | LTA4HMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30862011 | 0.72 | KDM4E (0.72) | LTA4HMEN1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |