Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | KLK1 | P06870 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069103 | 0.87 | L3MBTL1 (0.52) | KLKB1KLK1AOC3LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL4782319 | 0.86 | L3MBTL1 (0.51) | KLKB1KLK1AOC3LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL4736117 | 0.86 | L3MBTL1 (0.51) | KLKB1KLK1AOC3LMNAMAPK1 | |
| SCHEMBL11629636 | 0.79 | HDAC1 (0.57) | HDAC3HDAC1HDAC6HDAC2ERCC1 | |
| SCHEMBL9365919 | 0.77 | ERCC1 (0.59) | HDAC3HDAC1HDAC6HDAC2ERCC1 | |
| SCHEMBL8837372 | 0.76 | L3MBTL1 (0.74) | HDAC3HDAC1HDAC6ERCC1ERCC4 | |
| SCHEMBL4739798 | 0.76 | LTA4H (0.47) | HDAC1AOC3MAPK1 | |
| SCHEMBL8183769 | 0.76 | HDAC1 (0.58) | HDAC3HDAC1HDAC6HDAC2ERCC1 | |
| SCHEMBL10247918 | 0.76 | HPGDS (0.67) | HDAC3HDAC1HDAC6KLKB1KLK1 | |
| SCHEMBL27306145 | 0.75 | AOC3 (0.51) | HDAC1KLKB1KLK1AOC3NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |