Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737211 | 0.89 | CYP19A1 (0.34) | PTK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4737851 | 0.85 | CYP19A1 (0.32) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4735019 | 0.85 | NQO2 (0.38) | CYP19A1CYP11B2 | |
| SCHEMBL4735017 | 0.84 | — | — | |
| SCHEMBL4735621 | 0.84 | — | — | |
| SCHEMBL4734337 | 0.84 | DUSP10 (0.31) | — | |
| SCHEMBL4736286 | 0.84 | — | — | |
| SCHEMBL4735242 | 0.83 | FNTA (0.31) | — | |
| SCHEMBL4738139 | 0.81 | ACHE (0.35) | — | |
| SCHEMBL4738145 | 0.81 | ACHE (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071765-A1 | PHARMACEUTICALLY ACTIVE SPIRO-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |