Sumatrol

Sumatrol

SCHEMBL4739987

C=C(C)[C@H]1Cc2c(cc(O)c3c2O[C@@H]2COc4cc(OC)c(OC)cc4[C@@H]2C3=O)O1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 11/20 0.73
▸ MAPT P10636 8/20 0.73
▸ SMN1; SMN2 Q16637 8/20 0.73
▸ ALDH1A1 P00352 5/20 0.73
▸ KDM4E B2RXH2 5/20 0.73
▸ TDP1 Q9NUW8 5/20 0.73
▸ CYP2C19 P33261 4/20 0.73
▸ LMNA P02545 4/20 0.73
▸ MAPK1 P28482 4/20 0.73
▸ USP2 O75604 4/20 0.73
▸ TP53 P04637 4/20 0.73
▸ TSHR P16473 3/20 0.73
▸ MT-ND4 P03905 3/20 0.73
▸ CYP2C9 P11712 2/20 0.73
▸ NPC1 O15118 2/20 0.73
▸ RAB9A P51151 2/20 0.73
▸ CYP1A2 P05177 2/20 0.73
▸ HPGD P15428 2/20 0.73
▸ GMNN O75496 1/20 0.73
▸ ABCB11 O95342 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sumatrol SCHEMBL29929407 1.00 CYP3A4 (0.73) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
SCHEMBL6408904 0.89 CYP3A4 (0.73) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL13845713 0.84 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL29351552 0.84 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL29388856 0.84 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL42253 0.84 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL9815546 0.84 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL20152380 0.84 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL19019920 0.84 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL13926662 0.84 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250242030-A1 COMPOSITIONS COMPRISING A NON-BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2025-07-31 — — US claimed
US-20250135072-A1 COMPOSITIONS COMPRISING A BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2025-05-01 — — US claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US claimed
WO-2023147048-A1 COMPOSITIONS COMPRISING A BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2023-08-03 — — WO claimed
WO-2023147055-A1 COMPOSITIONS COMPRISING A NON-BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2023-08-03 — — WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2000062792-A2 COMPOSITIONS AND METHODS FOR CONTROLLING PESTS INSECT BIOTECHNOLOGY, INC. (US) 2000-10-26 — — WO claimed
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES NATURAL EXTRACTION SYS LLC (US) 2026-02-19 — — US disclosed
US-12409152-B2 Compositions and methods related to dissolved oxides Natural Extraction Systems, LLC (US) 2025-09-09 — — US disclosed
US-20250242030-A1 COMPOSITIONS COMPRISING A NON-BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2025-07-31 — — US disclosed
US-20250161394-A1 Compositions Comprising Kavalactones NATURAL EXTRACTION SYS LLC (US) 2025-05-22 — — US disclosed
US-20250135072-A1 COMPOSITIONS COMPRISING A BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2025-05-01 — — US disclosed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US disclosed
WO-2000062792-A2 COMPOSITIONS AND METHODS FOR CONTROLLING PESTS INSECT BIOTECHNOLOGY, INC. (US) 2000-10-26 — — WO disclosed
WO-1999063818-A1 USE OF AT LEAST ONE ACID FROM THE CITRIC ACID CYCLE COMBINED WITH GLYCERINE AS A PESTICIDE BIOLINK TECHNOLOGIES AG (CH) 1999-12-16 — — WO disclosed
US-5609878-A ADSORBENT POLYMER GUEYNE JEAN (MC) 1997-03-11 — — US disclosed
EP-0588857-B1 INSECTICIDE COMPOSITION GUEYNE JEAN (MC) 1997-01-15 — — EP disclosed
EP-0588857-A1 INSECTICIDE COMPOSITION. GUEYNE JEAN (MC) 1994-03-30 — — EP disclosed
WO-1992021242-A1 INSECTICIDE COMPOSITION GUEYNE JEAN (MC) 1992-12-10 — — WO disclosed
US-4690775-A Emulsion-based gel and process for preparing same RESEARCH CORPORATION (US) 1987-09-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12409152-B2 Compositions and methods related to dissolved oxides PRKG2, PRKG1, CIT CYP3A4 3252/4885MAPT 2118/4885SMN1; SMN2 3703/4885
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES SCO2, CNR2, CNR1 CYP3A4 1840/4885MAPT 3552/4885SMN1; SMN2 2953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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