Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786793 | 0.89 | CNR1 (0.47) | CNR1LMNAPOLBATAD2L3MBTL1 | |
| SCHEMBL4739847 | 0.87 | POLB (0.49) | LMNAPOLBATAD2L3MBTL1ACLY | |
| SCHEMBL4737502 | 0.87 | POLB (0.49) | LMNAPOLBATAD2L3MBTL1ACLY | |
| SCHEMBL4740214 | 0.85 | POLB (0.60) | CNR1POLBATAD2L3MBTL1ALDH1A1 | |
| SCHEMBL4738964 | 0.84 | POLB (0.51) | LMNAPOLBL3MBTL1ALDH1A1MAPT | |
| SCHEMBL4741097 | 0.84 | ALDH1A1 (0.51) | LMNAPOLBATAD2L3MBTL1ALDH1A1 | |
| SCHEMBL4740459 | 0.84 | ALDH1A1 (0.51) | LMNAPOLBATAD2L3MBTL1ALDH1A1 | |
| SCHEMBL4740901 | 0.83 | CYP19A1 (0.58) | LMNAPOLBL3MBTL1ALDH1A1MAPT | |
| SCHEMBL4740191 | 0.83 | ALDH1A1 (0.55) | EPHX2LMNAPOLBALDH1A1MAPT | |
| SCHEMBL4737402 | 0.83 | EPHX2 (0.62) | EPHX2LMNAALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |