Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.62 |
| ▸ | EBP | Q15125 | 2/20 | 0.48 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739860 | 0.84 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL4741708 | 0.83 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL4740140 | 0.83 | CNR1 (0.46) | EPHX2ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL4737578 | 0.83 | EPHX2 (0.49) | EPHX2ALDH1A1LMNA | |
| SCHEMBL4739879 | 0.82 | RAB9A (0.58) | ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL4741089 | 0.81 | LMNA (0.44) | EPHX2ALDH1A1MAPTLMNA | |
| SCHEMBL4740145 | 0.81 | MAPT (0.49) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL4787735 | 0.81 | CYP19A1 (0.58) | EPHX2ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL4740197 | 0.81 | LMNA (0.50) | ALDH1A1MAPTLMNA | |
| SCHEMBL4785880 | 0.80 | CYP3A4 (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |