Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785702 | 0.91 | MAPK1 (0.52) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL4786793 | 0.89 | CNR1 (0.47) | ALDH1A1LMNAMAPTPOLBDPP4 | |
| SCHEMBL4738964 | 0.87 | POLB (0.51) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL4736709 | 0.87 | LMNA (0.57) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL4737593 | 0.87 | LMNA (0.57) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL4741097 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL4740459 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL4741043 | 0.86 | KMT2A (0.58) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL4740901 | 0.86 | CYP19A1 (0.58) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL4737502 | 0.85 | POLB (0.49) | ALDH1A1KMT2AMEN1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |