Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741097 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTTSHRL3MBTL1GAA | |
| SCHEMBL4739879 | 0.92 | RAB9A (0.58) | ALDH1A1MAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL4740901 | 0.91 | CYP19A1 (0.58) | ALDH1A1MAPTTSHRL3MBTL1GAA | |
| SCHEMBL4740383 | 0.88 | SMN1; SMN2 (0.58) | ALDH1A1TSHRL3MBTL1GAAPOLB | |
| SCHEMBL4738964 | 0.88 | POLB (0.51) | ALDH1A1MAPTL3MBTL1GAAPOLB | |
| SCHEMBL4740191 | 0.86 | ALDH1A1 (0.55) | ALDH1A1MAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL4740214 | 0.86 | POLB (0.60) | ALDH1A1TSHRL3MBTL1POLBMEN1 | |
| SCHEMBL4786793 | 0.86 | CNR1 (0.47) | ALDH1A1MAPTL3MBTL1POLBLMNA | |
| SCHEMBL4739877 | 0.85 | TSHR (0.50) | TSHRL3MBTL1GAAPOLBMEN1 | |
| SCHEMBL4739899 | 0.84 | AKR1C3 (0.60) | MAPTTSHRGAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |