Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609526 | 0.90 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL16065515 | 0.84 | OPRM1 (0.38) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL373936 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL13755065 | 0.81 | SLC22A1 (0.39) | ALDH1A1POLBOPRM1SMN1; SMN2OPRD1 | |
| SCHEMBL12933673 | 0.81 | ALDH1A1 (0.35) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL15074623 | 0.78 | SMN1; SMN2 (0.38) | POLBOPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL5787834 | 0.78 | SMN1; SMN2 (0.42) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL7102497 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL11470013 | 0.77 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL12751319 | 0.77 | BRD4 (0.45) | ALDH1A1LMNAHSD17B10POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701704-B2 | Catalysts for (E)-selective olefin metathesis | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170022231-A1 | CATALYSTS FOR (E)-SELECTIVE OLEFIN METATHESIS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2017-01-26 | — | — | US | disclosed |
| US-8361922-B2 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins | MATERIA, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20120123133-A1 | ORGANOMETALLIC RUTHENIUM COMPLEXES AND RELATED METHODS FOR THE PREPARATION OF TETRA-SUBSTITUTED AND OTHER HINDERED OLEFINS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022231-A1 | CATALYSTS FOR (E)-SELECTIVE OLEFIN METATHESIS | COASY, FDFT1, SQLE | ALDH1A1 1299/4885LMNA 4006/4885HSD17B10 1070/4885 |
| US-20120123133-A1 | ORGANOMETALLIC RUTHENIUM COMPLEXES AND RELATED METHODS FOR THE PREPARATION OF TETRA-SUBSTITUTED AND OTHER HINDERED OLEFINS | ORC3, OXER1, CBR3 | ALDH1A1 2951/4885LMNA 4764/4885HSD17B10 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.