Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 10/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159836 | 0.81 | GABRA1 (0.39) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL28868370 | 0.81 | GABRA1 (0.38) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL4636005 | 0.79 | GABRA1 (0.37) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL5524714 | 0.78 | HPGDS (0.34) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL10067534 | 0.77 | ALDH1A1 (0.38) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL7373191 | 0.77 | GABRP (0.33) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL4747477 | 0.76 | GABRA1 (0.35) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL3794190 | 0.76 | GABRA1 (0.35) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL18048108 | 0.74 | LCK (0.37) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL8647610 | 0.73 | CYP1A2 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096360-A2 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2008-08-14 | — | — | WO | disclosed |