Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15952901 | 0.79 | MAPT (0.36) | MAPTLMNACYP2C9PTGS1AKR1C3 | |
| SCHEMBL1254149 | 0.78 | CES2 (0.39) | CYP2C9 | |
| SCHEMBL1233239 | 0.76 | — | — | |
| SCHEMBL4771428 | 0.76 | — | — | |
| Methylamine SCHEMBL8343939 | 0.74 | PTGS1 (0.39) | MAPTPARP1PARP15PARP10LMNA | |
| Urea SCHEMBL28496350 | 0.73 | LMNA (0.41) | MAPTPARP1PARP15PARP10LMNA | |
| Carbamic Acid SCHEMBL27546522 | 0.73 | ACHE (0.44) | MAPTPARP1PARP15PARP10LMNA | |
| SCHEMBL8059991 | 0.72 | — | — | |
| SCHEMBL10637923 | 0.70 | LDHA (0.44) | PARP1PARP15PARP10LMNAALOX15 | |
| Carbamic Acid SCHEMBL28286284 | 0.70 | ACHE (0.41) | PARP1PARP15PARP10LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085119-A1 | NEW PYRIDINE ANALOGUES VIII 518 | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |