Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TAS2R46 | P59540 | 6/20 | 0.33 |
| ▸ | TAS2R31 | P59538 | 2/20 | 0.33 |
| ▸ | TAS2R10 | Q9NYW0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472607 | 1.00 | LMNA (0.55) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL10831405 | 0.86 | LMNA (0.51) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL25622935 | 0.80 | LMNA (0.46) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL3930807 | 0.80 | LMNA (0.53) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL2431486 | 0.79 | LMNA (0.51) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL31601392 | 0.79 | LMNA (0.51) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL15450107 | 0.79 | LMNA (0.66) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL937050 | 0.79 | LMNA (0.60) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL12909964 | 0.79 | LMNA (0.66) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL1783157 | 0.79 | LMNA (0.66) | LMNATSHRALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461320-B1 | ENANTIOSELECTIVE TRANSFORMATION OF ALFA,BETA-UNSATURATED KETONES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2008-04-09 | — | — | EP | disclosed |