Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31601392 | 0.81 | LMNA (0.51) | LMNATSHRRAB9AALDH1A1NPC1 | |
| SCHEMBL2431486 | 0.81 | LMNA (0.51) | LMNATSHRRAB9AALDH1A1NPC1 | |
| SCHEMBL4740720 | 0.80 | LMNA (0.55) | LMNATSHRRAB9AALDH1A1NPC1 | |
| SCHEMBL4472607 | 0.80 | LMNA (0.55) | LMNATSHRRAB9AALDH1A1NPC1 | |
| SCHEMBL10831405 | 0.78 | LMNA (0.51) | LMNATSHRRAB9AALDH1A1NPC1 | |
| (-)-Limonene SCHEMBL1273506 | 0.76 | LMNA (0.63) | LMNATSHRRAB9AALDH1A1NPC1 | |
| SCHEMBL1014646 | 0.76 | GAA (0.58) | LMNARAB9AALDH1A1MGAMGAA | |
| SCHEMBL15182066 | 0.75 | SMN1; SMN2 (0.49) | LMNATSHRRAB9AALDH1A1MGAM | |
| SCHEMBL17036172 | 0.75 | MGAM (0.44) | LMNATSHRRAB9AALDH1A1MGAM | |
| D-Limonene SCHEMBL8318907 | 0.75 | LMNA (0.71) | LMNATSHRRAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183186-A1 | PYRIMIDINE CYCLOHEXENYL GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS INCORPORATED | 2023-06-15 | — | — | US | disclosed |
| US-9671392-B2 | Multisensor array for detection of analytes or mixtures thereof in gas or liquid phase | DANMARKS TEKNISKE UNIVERSITET (DK) | 2017-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183186-A1 | PYRIMIDINE CYCLOHEXENYL GLUCOCORTICOID RECEPTOR MODULATORS | NR3C1, NR3C2, MC2R | LMNA 4762/4885TSHR 216/4885RAB9A 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.