Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12716163 | 0.84 | TXNRD1 (0.52) | TXNRD1ELANEKMT2AHTTHPGD | |
| SCHEMBL16638891 | 0.82 | TXNRD1 (0.67) | TXNRD1ELANEKMT2AHTTTHRB | |
| SCHEMBL1998230 | 0.82 | CA12 (0.59) | TXNRD1ELANEHPGDL3MBTL1LMNA | |
| SCHEMBL14511069 | 0.82 | TXNRD1 (0.50) | TXNRD1ELANEKMT2AHTTTHRB | |
| SCHEMBL7177043 | 0.79 | TXNRD1 (0.47) | TXNRD1ELANEKMT2AHTTL3MBTL1 | |
| SCHEMBL1994212 | 0.76 | CA12 (0.55) | TXNRD1ELANEHPGDLMNAKDM4E | |
| SCHEMBL22545515 | 0.73 | ALDH1A1 (0.47) | TXNRD1ELANEKMT2ATHRBLMNA | |
| SCHEMBL26657525 | 0.73 | CES2 (0.47) | TXNRD1ELANEKMT2ALMNAMEN1 | |
| SCHEMBL30294756 | 0.72 | CA12 (0.51) | TXNRD1ELANEL3MBTL1KDM4ECA12 | |
| SCHEMBL22853023 | 0.72 | CA12 (0.51) | TXNRD1ELANEL3MBTL1KDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079408-A1 | A ZEBRAFISH BASED SCREEN FOR AGENTS WITH ABILITY TO PREVENT CELL DEATH | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2008-07-03 | — | — | WO | claimed |
| WO-2008079408-A1 | A ZEBRAFISH BASED SCREEN FOR AGENTS WITH ABILITY TO PREVENT CELL DEATH | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2008-07-03 | — | — | WO | disclosed |
| US-6921633-B2 | Methods and compositions for the preservation of cells, tissues or organs in the vitreous state | BIOLIFE SOLUTIONS INCORPORATED (US) | 2005-07-26 | — | — | US | disclosed |
| WO-2004046308-A2 | METHODS AND COMPOSITIONS FOR THE PRESERVATION OF CELLS, TISSUES OR ORGANS IN THE VITREOUS STATE | BIOLIFE SOLUTIONS, INC. (US) | 2004-06-03 | — | — | WO | disclosed |
| US-20040096813-A1 | Methods and compositions for the preservation of cells, tissues or organs in the vitreous state | BIOLIFE SOLUTIONS, INC. | 2004-05-20 | — | — | US | disclosed |
| US-6576614-B1 | Administering methyl ketones or closed hemiketal derivatives of aspartic acid | VERTEX PHARMACEUTICALS INCORPORATED | 2003-06-10 | — | — | US | disclosed |
| US-5985838-A | TREATING INFECTIOUS DISEASE, RESPIRATORY DISEASE, INFLAMMATORY CONDITIONS, IMMUNE-BASED DISEASE, AUTO-IMMUNE DISEASE, BONE DISEASE, AND TUMORS | VERTEX PHARMACEUTICALS, INC. (US) | 1999-11-16 | — | — | US | disclosed |