Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYTH2 | Q99418 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23539085 | 0.86 | GAA (0.47) | CYTH2GAAKMT2AMEN1G6PD | |
| SCHEMBL10870818 | 0.85 | KMT2A (0.52) | KMT2AMEN1CYP1A2LMNAPOLB | |
| SCHEMBL2552398 | 0.84 | LMNA (0.61) | GAAKMT2AMEN1G6PDL3MBTL1 | |
| SCHEMBL21625694 | 0.80 | TOP1 (0.52) | GAAKMT2AMEN1G6PDL3MBTL1 | |
| SCHEMBL6864047 | 0.79 | ALDH1A1 (0.41) | GAAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL29177228 | 0.79 | SOS1 (0.41) | GAAKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL19847021 | 0.79 | KMT2A (0.55) | GAAKMT2AMEN1G6PDL3MBTL1 | |
| SCHEMBL13210692 | 0.79 | GAA (0.58) | GAAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL27801542 | 0.79 | TGM2 (0.58) | GAAKMT2AMEN1G6PDL3MBTL1 | |
| SCHEMBL11705452 | 0.78 | KMT2A (0.69) | GAAKMT2AMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |