Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | ACHE | P22303 | 3/20 | 0.60 |
| ▸ | MGAM | O43451 | 1/20 | 0.60 |
| ▸ | SI | P14410 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464004 | 0.82 | GAA (0.53) | GAAACHEMGAMSIPTPN1 | |
| SCHEMBL23302557 | 0.78 | GAA (0.61) | GAAACHEMGAMSIPTPN1 | |
| SCHEMBL4744447 | 0.78 | GAA (0.61) | GAAACHEMGAMSIPTPN1 | |
| SCHEMBL9463889 | 0.76 | ALDH2 (0.60) | GAAALDH1A1KDM4EHPGDHSD17B10 | |
| Decursinol SCHEMBL18845442 | 0.75 | GAA (1.00) | GAAACHEMGAMSIPTPN1 | |
| Decursinol SCHEMBL29517185 | 0.75 | GAA (1.00) | GAAACHEMGAMSIPTPN1 | |
| Decursinol SCHEMBL30034733 | 0.75 | GAA (1.00) | GAAACHEMGAMSIPTPN1 | |
| Decursinol SCHEMBL14105325 | 0.75 | GAA (1.00) | GAAACHEMGAMSIPTPN1 | |
| SCHEMBL14105337 | 0.75 | GAA (0.76) | GAAACHEMGAMSIPTPN1 | |
| Decursinol SCHEMBL3895912 | 0.75 | GAA (1.00) | GAAACHEMGAMSIPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277297-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-11-01 | — | — | US | claimed |
| EP-2001463-A1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | Council of Scientific and Industrial Research (IN) | 2008-12-17 | — | — | EP | claimed |
| WO-2008102994-A1 | COMPOSITION COMPRISING DECURSIN DERIVATIVE FOR TREATING AND PREVENTING ATOPIC DERMATITIS | PARK YONG JIN (KR) | 2008-08-28 | — | — | WO | claimed |
| US-20080009544-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-01-10 | — | — | US | claimed |
| WO-2007107846-A1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-27 | — | — | WO | claimed |
| WO-1990008529-A2 | 7-ALKOXYCOUMARINS, DIHYDROPSORALENS, AND BENZODIPYRANONES AS PHOTO-ACTIVATED THERAPEUTIC AGENTS AND INHIBITORS OF EPIDERMAL GROWTH FACTOR | LEHIGH UNIVERSITY (US) | 1990-08-09 | — | — | WO | claimed |
| WO-2024172513-A1 | NOVEL DECURSIN DERIVATIVE AND USE THEREOF FOR PREVENTING OR TREATING NON-SMALL CELL LUNG CANCER | (주)재인알앤피 | 2024-08-22 | — | — | WO | disclosed |
| WO-2022154356-A1 | COMPOSITION COMPRISING (7S)-(+)-CYCLOPENTYL CARBARMIC ACID, 8,8-DIMETHYL-2-OXO-6,7-DIHYDRO-2H,8H-PYRANO[3,2-G]CHROMEN-7-YL-ESTER AS ACTIVE INGREDIENT FOR PREVENTION, ALLEVIATION, OR TREATMENT OF EYE DISEASE | 국민대학교 산학협력단 | 2022-07-21 | — | — | WO | disclosed |
| US-20170129904-A1 | NEW COMPOUND FOR INHIBITING BINDING BETWEEN DX2 PROTEIN AND P14/ARF PROTEIN, AND PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER DISEASE CONTAINING SAME AS EFFECTIVE INGREDIENT | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2017-05-11 | — | — | US | disclosed |
| US-20170129904-A1 | NEW COMPOUND FOR INHIBITING BINDING BETWEEN DX2 PROTEIN AND P14/ARF PROTEIN, AND PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER DISEASE CONTAINING SAME AS EFFECTIVE INGREDIENT | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2017-05-11 | — | — | US | disclosed |
| EP-2001463-B1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | COUNCIL SCIENT IND RES (IN) | 2013-07-03 | — | — | EP | disclosed |
| EP-2001463-B1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | COUNCIL SCIENT IND RES (IN) | 2013-07-03 | — | — | EP | disclosed |
| CN-101437510-B | A pharmaceutical composition useful as acetyl cholinesterase inhibitors | COUNCIL SCIENT IND RES | 2012-12-05 | — | — | CN | disclosed |
| US-20080009544-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-01-10 | — | — | US | disclosed |
| US-20080009544-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-01-10 | — | — | US | disclosed |
| WO-2007107846-A1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007107846-A1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007107846-A1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-27 | — | — | WO | disclosed |
| US-5216176-A | 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor | LEHIGH UNIVERSITY (US) | 1993-06-01 | — | — | US | disclosed |
| WO-1990008529-A2 | 7-ALKOXYCOUMARINS, DIHYDROPSORALENS, AND BENZODIPYRANONES AS PHOTO-ACTIVATED THERAPEUTIC AGENTS AND INHIBITORS OF EPIDERMAL GROWTH FACTOR | LEHIGH UNIVERSITY (US) | 1990-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009544-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | ACHE, BCHE, CHRNB1 | GAA 489/4885ACHE 1/4885MGAM 1102/4885 |
| US-20120277297-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | ACHE, BCHE, CYP3A7 | GAA 440/4885ACHE 1/4885MGAM 2152/4885 |
| US-20170129904-A1 | NEW COMPOUND FOR INHIBITING BINDING BETWEEN DX2 PROTEIN AND P14/ARF PROTEIN, AND PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER DISEASE CONTAINING SAME AS EFFECTIVE INGREDIENT | ARFIP2, G3BP2, TPX2 | GAA 3451/4885ACHE 4685/4885MGAM 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.