Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738537 | 0.86 | TYMS (0.65) | TYMS | |
| SCHEMBL4738561 | 0.84 | TSHR (0.48) | ALDH1A1 | |
| SCHEMBL4741147 | 0.79 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL4737442 | 0.77 | MAPT (0.41) | ALDH1A1 | |
| SCHEMBL4741212 | 0.75 | KMT2A (0.49) | ALDH1A1 | |
| SCHEMBL4787519 | 0.73 | TSHR (0.46) | ALDH1A1 | |
| SCHEMBL4739962 | 0.72 | TYMS (0.82) | TYMS | |
| Hydrochloric Acid SCHEMBL6648356 | 0.71 | TYMS (0.80) | TYMS | |
| SCHEMBL6655151 | 0.70 | TYMS (1.00) | TYMS | |
| SCHEMBL6652286 | 0.69 | TYMS (1.00) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008086158-A1 | BENZODIHYDROQUINAZOLINE AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008086158-A1 | BENZODIHYDROQUINAZOLINE AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-17 | — | — | WO | disclosed |