Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.45 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14100610 | 0.89 | GSTO1 (0.45) | TDP1SMN1; SMN2KMT2AMEN1SFRP1 | |
| SCHEMBL14100395 | 0.87 | TDP1 (0.66) | TDP1SMN1; SMN2KMT2AMEN1SFRP1 | |
| SCHEMBL4741863 | 0.84 | GSTO1 (0.60) | TDP1SMN1; SMN2KMT2AMEN1GSTO1 | |
| SCHEMBL22499575 | 0.83 | TDP1 (0.53) | TDP1SMN1; SMN2KMT2AMAPTTP53 | |
| SCHEMBL29400012 | 0.83 | TDP1 (0.53) | TDP1SMN1; SMN2KMT2AMAPTTP53 | |
| SCHEMBL4741871 | 0.79 | HSD17B10 (0.42) | TDP1KMT2AMEN1GSTO1ALDH1A1 | |
| SCHEMBL22499574 | 0.74 | TDP1 (0.40) | TDP1SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL29384429 | 0.74 | TDP1 (0.40) | TDP1SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL26144861 | 0.74 | MAPT (0.72) | TDP1SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL4741864 | 0.73 | KMT2A (0.49) | KMT2AMEN1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098025-A1 | ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008098025-A1 | ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |