Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3020549 | 0.86 | MEN1 (0.54) | KMT2AMEN1PKMRAB9ATRPV4 | |
| SCHEMBL12656085 | 0.83 | KMT2A (0.51) | KMT2AMEN1PKMRAB9ATRPV4 | |
| SCHEMBL2964467 | 0.83 | KMT2A (0.49) | KMT2AMEN1PKMRAB9ATRPV4 | |
| SCHEMBL840799 | 0.82 | CNR2 (0.57) | KMT2AMEN1PKMRAB9ATRPV4 | |
| SCHEMBL12655990 | 0.81 | L3MBTL1 (0.48) | KMT2AMEN1PKMRAB9ATRPV4 | |
| SCHEMBL12656087 | 0.80 | RAB9A (0.44) | KMT2AMEN1PKMRAB9ATRPV4 | |
| SCHEMBL4741871 | 0.77 | HSD17B10 (0.42) | KMT2AMEN1CNR1EPHX2S1PR1 | |
| SCHEMBL12622152 | 0.76 | L3MBTL1 (0.43) | KMT2AMEN1PKMRAB9ATRPV4 | |
| SCHEMBL5442261 | 0.74 | TGM2 (0.52) | KMT2AMEN1EPHX2ALDH1A1 | |
| SCHEMBL2635081 | 0.74 | PKM (0.45) | KMT2AMEN1PKMRAB9ATRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098025-A1 | ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008098025-A1 | ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |