Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14100591 | 0.89 | GSTO1 (0.62) | GSTO1PKMALDH1A1LMNATSHR | |
| SCHEMBL14100395 | 0.88 | TDP1 (0.66) | SMN1; SMN2NPC1RAB9ATDP1KMT2A | |
| SCHEMBL7664954 | 0.84 | PKM (0.61) | PKMALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4741333 | 0.84 | TDP1 (0.50) | GSTO1ALDH1A1SMN1; SMN2TDP1KMT2A | |
| SCHEMBL4717858 | 0.83 | LMNA (0.70) | PKMALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL7659574 | 0.81 | PKM (0.61) | PKMALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4716079 | 0.81 | TDP1 (0.76) | PKMALDH1A1SMN1; SMN2RAB9ATDP1 | |
| SCHEMBL4252422 | 0.80 | SMN1; SMN2 (0.77) | PKMALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3406021 | 0.80 | GSTO1 (0.61) | GSTO1PKMALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3949541 | 0.80 | CNR2 (0.66) | PKMALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098025-A1 | ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008098025-A1 | ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |