Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739897 | 0.86 | ALDH1A1 (0.39) | HSD17B10KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL4739150 | 0.85 | GSTO1 (0.50) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL4741333 | 0.79 | TDP1 (0.50) | KMT2AMEN1ALDH1A1TDP1GSTO1 | |
| SCHEMBL4741864 | 0.77 | KMT2A (0.49) | KMT2AMEN1ALDH1A1L3MBTL1CNR1 | |
| SCHEMBL14100610 | 0.73 | GSTO1 (0.45) | KMT2AMEN1ALDH1A1LMNATDP1 | |
| SCHEMBL24478422 | 0.70 | ALOX5AP (0.41) | HSD17B10KMT2AMEN1CA12CA1 | |
| SCHEMBL31494280 | 0.70 | ALOX5AP (0.41) | HSD17B10KMT2AMEN1CA12CA1 | |
| SCHEMBL11173490 | 0.69 | MEN1 (0.76) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11173862 | 0.68 | POLB (0.65) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL15915525 | 0.67 | POLB (0.55) | KMT2AMEN1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098025-A1 | ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008098025-A1 | ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |