Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4238123 | 0.96 | MAPT (0.45) | MCHR1MAPTL3MBTL1KITFLT3 | |
| SCHEMBL4234174 | 0.90 | PKM (0.43) | FLT3 | |
| SCHEMBL4236614 | 0.88 | MAPT (0.52) | MCHR1MAPTL3MBTL1MCHR2CCR5 | |
| SCHEMBL4229322 | 0.87 | MCHR1 (0.46) | MCHR1MAPTL3MBTL1KITFLT3 | |
| SCHEMBL4236550 | 0.85 | MCHR1 (0.40) | MCHR1MAPTL3MBTL1MCHR2HSD17B10 | |
| SCHEMBL4233481 | 0.84 | HRH3 (0.47) | FLT3 | |
| SCHEMBL4238765 | 0.84 | HRH3 (0.47) | FLT3 | |
| SCHEMBL4233537 | 0.82 | MAPT (0.50) | MCHR1MAPTL3MBTL1CCR5HSD17B10 | |
| SCHEMBL4687968 | 0.82 | DRD2 (0.37) | MCHR1KITFLT3MCHR2CCR5 | |
| SCHEMBL4236654 | 0.81 | PKM (0.47) | MCHR1MAPTALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |