Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 5/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741711 | 0.91 | SSTR5 (0.36) | DRD2ADRA1AGHSRBCL9CTNNB1 | |
| SCHEMBL4741716 | 0.90 | CCR5 (0.35) | DRD2ADRA1AGHSRBCL9CTNNB1 | |
| SCHEMBL4232938 | 0.89 | BCL9 (0.43) | BCL9CTNNB1 | |
| SCHEMBL4229322 | 0.84 | MCHR1 (0.46) | MCHR1GSK3BKITFLT3ACKR3 | |
| SCHEMBL4238724 | 0.84 | MCHR1 (0.37) | DRD2ADRA1ABCL9CTNNB1MCHR1 | |
| SCHEMBL4236545 | 0.84 | MCHR1 (0.34) | DRD2ADRA1ABCL9CTNNB1MCHR1 | |
| SCHEMBL4741586 | 0.82 | MCHR1 (0.42) | DRD2MCHR1GSK3BKITFLT3 | |
| SCHEMBL4242203 | 0.79 | ACKR3 (0.42) | MCHR1GSK3BACKR3CCR5 | |
| SCHEMBL4228647 | 0.79 | PKM (0.43) | BCL9CTNNB1GSK3BFLT3 | |
| SCHEMBL4228632 | 0.79 | MCHR1 (0.39) | DRD2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |