Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRPS1 | P60891 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21025786 | 0.88 | TGFBR1 (0.43) | PRPS1TP53TSHRKCNH2LMNA | |
| SCHEMBL19848146 | 0.85 | LMNA (0.56) | PRPS1TP53TSHRLMNAMAPT | |
| SCHEMBL19848506 | 0.82 | PRPS1 (0.51) | PRPS1NPC1RAB9ALMNANPSR1 | |
| SCHEMBL18731437 | 0.81 | LMNA (0.47) | TP53LMNAMAPTMEN1KMT2A | |
| SCHEMBL11347338 | 0.80 | PRPS1 (0.48) | PRPS1NPC1HTR1ATBXA2RRAB9A | |
| SCHEMBL18731877 | 0.80 | EGFR (0.48) | TP53NPC1RAB9ALMNAMAPT | |
| SCHEMBL21025781 | 0.80 | HTR6 (0.42) | PRPS1CYP1A2KCNH2LMNAMAPT | |
| SCHEMBL19915934 | 0.79 | PRPS1 (0.45) | PRPS1LMNAQPCTCNR2 | |
| SCHEMBL21026260 | 0.77 | MAPT (0.48) | TP53KCNH2LMNAMAPTTDP1 | |
| SCHEMBL10025500 | 0.77 | FGFR1 (0.54) | TP53NPC1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |