Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 8/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | USP1 | O94782 | 2/20 | 0.30 |
| ▸ | LYN | P07948 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741763 | 0.91 | KDM4E (0.35) | PDE2APOLBSMN1; SMN2USP1LYN | |
| SCHEMBL4742985 | 0.85 | USP1 (0.36) | MDM2USP1 | |
| SCHEMBL4743760 | 0.84 | USP1 (0.32) | POLBMAPTMETMDM2USP1 | |
| SCHEMBL4485590 | 0.80 | TP53 (0.33) | POLBTP53MAPTSMN1; SMN2MDM2 | |
| SCHEMBL3993899 | 0.80 | TP53 (0.33) | POLBTP53MAPTSMN1; SMN2MDM2 | |
| SCHEMBL4489726 | 0.79 | KDM4E (0.30) | SMN1; SMN2 | |
| SCHEMBL4482238 | 0.78 | LYN (0.32) | MAPTLYN | |
| SCHEMBL4489281 | 0.77 | KCNH2 (0.34) | SMN1; SMN2USP1 | |
| SCHEMBL4484643 | 0.77 | WEE1 (0.30) | — | |
| SCHEMBL4742187 | 0.76 | USP1 (0.33) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107398-A2 | PYRAZINE COMPOUNDS | BASF SE (DE) | 2008-09-12 | — | — | WO | disclosed |