SCHEMBL4742280

SCHEMBL4742280

Cc1cc(=O)n(-c2ncccn2)c(O)c1/N=N/c1c(C#N)cnn1-c1ncccn1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
KMT2A Q03164 1/20 0.32
DPP4 P27487 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4743198 0.77 MAPT (0.38) KMT2AALDH1A1LMNATDP1
SCHEMBL4742259 0.77 MAPT (0.38) KMT2AALDH1A1LMNATDP1
SCHEMBL4742613 0.75 HTT (0.35) KMT2AALDH1A1LMNATSHRTDP1
SCHEMBL4742276 0.75 KMT2A (0.41) KMT2ALMNATDP1
SCHEMBL4742303 0.74 DPP4 (0.36) RXRARXRBRXRGKMT2ADPP4
SCHEMBL4742576 0.73 SMN1; SMN2 (0.36) DPP4ALDH1A1LMNATSHRTDP1
SCHEMBL10101841 0.73 NPC1 (0.30)
SCHEMBL4742643 0.73 SMN1; SMN2 (0.36) DPP4ALDH1A1LMNATSHRTDP1
SCHEMBL4742302 0.73
SCHEMBL4742563 0.72 MAPT (0.36) KMT2ADPP4ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed