SCHEMBL4742613

SCHEMBL4742613

Cc1ccc(-n2[nH]c(=O)c(N=Nc3c(C#N)cnn3-c3ncccn3)c2O)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.35
GRM7 Q14831 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742563 0.83 MAPT (0.36) HTTALDH1A1LMNATSHRTDP1
SCHEMBL4742610 0.80
SCHEMBL4742280 0.75 RXRA (0.32) ALDH1A1LMNATSHRTDP1KMT2A
SCHEMBL4742612 0.74 FFAR4 (0.36) LMNATDP1SMN1; SMN2KMT2AMEN1
SCHEMBL4742276 0.72 KMT2A (0.41) LMNATDP1SMN1; SMN2KMT2AMEN1
SCHEMBL4742259 0.71 MAPT (0.38) ALDH1A1LMNATDP1SMN1; SMN2KMT2A
SCHEMBL4743198 0.71 MAPT (0.38) ALDH1A1LMNATDP1SMN1; SMN2KMT2A
SCHEMBL2743041 0.69 RAB9A (0.43) HTTALDH1A1LMNASMN1; SMN2KMT2A
SCHEMBL4742168 0.69 LMNA (0.42) HTTALDH1A1LMNATSHRTDP1
SCHEMBL4742576 0.69 SMN1; SMN2 (0.36) HTTALDH1A1LMNATSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed