SCHEMBL4742528

SCHEMBL4742528

CNS(=O)(=O)Nc1cc(N2CCCCC2)ccc1/N=N/c1c(C#N)cnn1-c1nc(CO)nc(OC)n1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
ACLY P53396 1/20 0.31
SUV39H2 Q9H5I1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742452 0.75 ALDH1A1 (0.37) ALDH1A1LMNATSHRTDP1
SCHEMBL4742437 0.71 ALDH1A1 (0.38) ALDH1A1LMNATSHRTDP1
SCHEMBL4742439 0.70 ALDH1A1 (0.38) ALDH1A1LMNATSHRTDP1
SCHEMBL13635016 0.59 CSF1R (0.32) ALDH1A1LMNAACLY
SCHEMBL13900701 0.59 CSF1R (0.31) ALDH1A1LMNAACLY
SCHEMBL4742501 0.58 KCNH2 (0.39) ALDH1A1TDP1
SCHEMBL4742456 0.58 RAB9A (0.50) ALDH1A1LMNATSHRTDP1
SCHEMBL14562260 0.58 LMNA (0.32) LMNA
SCHEMBL14418226 0.58 LMNA (0.32) LMNA
SCHEMBL15694830 0.56 XDH (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed