Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739339 | 0.88 | MET (0.46) | METALDH1A1MAPTLMNAPDGFRB | |
| SCHEMBL4742105 | 0.88 | THRB (0.45) | METMAPTPDGFRBPTPN11SMN1; SMN2 | |
| SCHEMBL4786909 | 0.85 | MET (0.39) | METALDH1A1MAPTLMNAPTPN11 | |
| SCHEMBL4742143 | 0.80 | ALDH1A1 (0.58) | METALDH1A1MAPTLMNAPDGFRB | |
| SCHEMBL4742558 | 0.80 | USP2 (0.44) | METMAPTLMNAPTPN11SMN1; SMN2 | |
| SCHEMBL4743466 | 0.78 | THRB (0.46) | ALDH1A1MAPTSMN1; SMN2TSHRTHRB | |
| SCHEMBL4742104 | 0.78 | MAPT (0.53) | METALDH1A1MAPTLMNAPDGFRB | |
| SCHEMBL4785479 | 0.77 | THRB (0.42) | METALDH1A1MAPTLMNAKIT | |
| SCHEMBL4743406 | 0.73 | MET (0.39) | METALDH1A1MAPTLMNAKIT | |
| SCHEMBL5637927 | 0.70 | ALDH1A1 (0.60) | METALDH1A1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093940-A1 | QUINOLINE DERIVATIVES AS CASPASE-3 INHIBITOR, PREPARATION PROCESS FOR THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |