Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785479 | 0.89 | THRB (0.42) | METMAPTALDH1A1LMNAPTPN11 | |
| SCHEMBL4742589 | 0.88 | MET (0.44) | METMAPTALDH1A1LMNAKCNH2 | |
| SCHEMBL4743406 | 0.85 | MET (0.39) | METMAPTALDH1A1LMNAPTPN11 | |
| SCHEMBL4742143 | 0.80 | ALDH1A1 (0.58) | METMAPTALDH1A1LMNAKCNH2 | |
| SCHEMBL4743037 | 0.80 | MAPT (0.40) | MAPTLMNAPTPN11THRBKIT | |
| SCHEMBL4742118 | 0.80 | MET (0.38) | METMAPTALDH1A1LMNATHRB | |
| SCHEMBL4742621 | 0.79 | USP2 (0.45) | METMAPTLMNAPTPN11SMN1; SMN2 | |
| SCHEMBL4785468 | 0.79 | THRB (0.45) | METTHRB | |
| SCHEMBL4743062 | 0.79 | THRB (0.47) | MAPTALDH1A1THRBSMN1; SMN2TSHR | |
| SCHEMBL4742104 | 0.79 | MAPT (0.53) | METMAPTALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093940-A1 | QUINOLINE DERIVATIVES AS CASPASE-3 INHIBITOR, PREPARATION PROCESS FOR THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |