SCHEMBL4742894

SCHEMBL4742894

O=C(O)c1c(C2NCCO2)ccc2c1Cc1ccccc1O2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
ACSL1 P33121 1/20 0.35
ALOX5 P09917 3/20 0.33
GSR P00390 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SLC6A2 P23975 1/20 0.30
ADRA1A P35348 1/20 0.30
HTR2B P41595 1/20 0.30
SLC6A3 Q01959 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC10 Q969S8 1/20 0.30
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742286 0.82 DRD2 (0.38) MAOAMAOBACSL1DRD2DRD3
SCHEMBL9056290 0.76 ACSL1 (0.40) MAOAMAOBACSL1CYP2C9
SCHEMBL9057696 0.76 ACSL1 (0.40) MAOAMAOBACSL1CYP2C9
SCHEMBL83906 0.76 MAOA (0.48) MAOAMAOBACSL1ALOX5GSR
SCHEMBL1672256 0.72 MAOA (0.47) MAOAMAOBACSL1ALOX5GSR
SCHEMBL4298022 0.72 MAOA (0.47) MAOAMAOBACSL1ALOX5GSR
SCHEMBL11506362 0.71 MAOA (0.46) MAOAMAOBACSL1ALOX5GSR
SCHEMBL2313646 0.71 MAOA (0.46) MAOAMAOBACSL1ALOX5GSR
SCHEMBL6680447 0.70 HPGD (0.41) MAOAMAOBACSL1CYP2C9KDM4E
SCHEMBL5692 0.70 MAOA (0.52) MAOAMAOBACSL1ALOX5CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008113814-A1 ORGANIC MOLYBDENUM COMPOUNDS, USE THEREOF AS FRICTION- MODIFIERS AND LUBRICATING COMPOSITIONS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2008-09-25 WO disclosed