Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.64 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670709 | 0.89 | CHRNB2 (0.59) | CHRNB2CHRNA4ALDH1A1GAAHRH3 | |
| SCHEMBL10803161 | 0.80 | ALDH1A1 (0.54) | CHRNB2CHRNA4ALDH1A1APPCYP1A2 | |
| SCHEMBL17911731 | 0.80 | CYP1A2 (0.58) | ALDH1A1APPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10768214 | 0.79 | CYP1A2 (0.64) | ALDH1A1APPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19420119 | 0.79 | PYCR1 (0.47) | CHRNB2CHRNA4APPCYP1A2CYP3A4 | |
| SCHEMBL8136691 | 0.78 | CYP2A6 (0.61) | ALDH1A1APPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL46986 | 0.77 | CHRNB2 (0.49) | CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL22962849 | 0.77 | CYP1A2 (0.50) | CHRNB2CHRNA4ALDH1A1APPCYP1A2 | |
| SCHEMBL614578 | 0.77 | CYP1A2 (0.50) | ALDH1A1APPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL613220 | 0.76 | CYP1A2 (0.54) | ALDH1A1APPCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096094-A1 | BICYCLOR[2.2.1]HEPT-7-YLAMINE DERIVATIVES AS MUSCARINIC M3 RECEPTOR MODULATORS | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |