Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742897 | 0.89 | CHRNB2 (0.64) | CHRNB2CHRNA4HRH3ALDH1A1GAA | |
| SCHEMBL18714798 | 0.81 | CHRNB2 (0.44) | CHRNB2CHRNA4HRH3NOS3NOS1 | |
| SCHEMBL3365259 | 0.80 | KEAP1 (0.47) | CHRNB2CHRNA4HRH3NOS3NOS1 | |
| SCHEMBL3365265 | 0.80 | APP (0.44) | CHRNB2CHRNA4HRH3ALDH1A1FFAR1 | |
| SCHEMBL3907916 | 0.78 | HRH3 (0.76) | HRH3ALDH1A1 | |
| SCHEMBL8846653 | 0.76 | FFAR1 (0.51) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL15807616 | 0.75 | PTPN2 (0.44) | CHRNB2CHRNA4KCNH2 | |
| SCHEMBL5886588 | 0.73 | FFAR1 (0.53) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL20982677 | 0.72 | ALDH1A1 (0.46) | CHRNB2CHRNA4NOS3NOS1NOS2 | |
| SCHEMBL15978587 | 0.70 | KDM4E (0.69) | HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093370-A | Useful prior to insertion of tracheotomy tube or discission | TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |