SCHEMBL4742903

SCHEMBL4742903

O=Cc1c(O)cc(O)c(C(=O)C=CC2C=CC=CC2)c1O

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.37
MAPT P10636 1/20 0.37
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2493332 0.81 MEN1 (0.42) CYP3A4MAPT
SCHEMBL4742843 0.76 MAOA (0.47) CYP3A4MAPTUSP2
SCHEMBL1844264 0.75 ABCB1 (0.34)
SCHEMBL1938572 0.73 MAPT (0.50) CYP3A4MAPTUSP2
SCHEMBL1937965 0.72 ABCG2 (0.54) CYP3A4MAPTUSP2
SCHEMBL28098802 0.70 CYP3A4 (0.48) CYP3A4MAPT
SCHEMBL23849510 0.70 ABCB1 (0.41)
SCHEMBL30132716 0.69 MAPT (0.45) CYP3A4MAPT
SCHEMBL28417375 0.69 MAPT (0.45) CYP3A4MAPT
SCHEMBL30132715 0.69 MAPT (0.45) CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2858641-B1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF CORP (US) 2017-09-06 EP claimed
EP-2888012-B1 ORAL CARE UNIV PRETORIA (ZA) 2020-06-17 EP disclosed
EP-2888012-A2 ORAL CARE University of Pretoria (ZA) 2015-07-01 EP disclosed
US-20150174059-A1 ORAL CARE UNIVERSITY OF PRETORIA (ZA) 2015-06-25 US disclosed
WO-2014033625-A2 ORAL CARE UNIVERSITY OF PRETORIA (ZA) 2014-03-06 WO disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150174059-A1 ORAL CARE NOP2, POLR1C, DPM1 CYP3A4 1844/4885MAPT 2090/4885USP2 4433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.