SCHEMBL4743005

SCHEMBL4743005

CC(=O)C(N=Nc1c(C#N)cnn1-c1ncccn1)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F11 P03951 3/20 0.37
KLKB1 P03952 3/20 0.37
MAPT P10636 8/20 0.34
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 4/20 0.33
MAPK1 P28482 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LRRK2 Q5S007 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4781297 0.88 PANK3 (0.34)
SCHEMBL4742949 0.84 PKM (0.39) MAPTKDM4EALDH1A1GAAMEN1
SCHEMBL4742772 0.82 TDP1 (0.37) F11KLKB1MAPTKDM4EALDH1A1
SCHEMBL4743047 0.81 PANK3 (0.30)
SCHEMBL4781307 0.80 GRM4 (0.32) KDM4EALDH1A1GAA
SCHEMBL4768039 0.79 THRB (0.32)
SCHEMBL4742936 0.79 LMNA (0.38) MAPTKDM4EALDH1A1GAAKMT2A
SCHEMBL4742972 0.78 POLB (0.41) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL4742942 0.78 HTT (0.36) MAPTKDM4EALDH1A1GAAMEN1
SCHEMBL4742963 0.78 HTT (0.36) MAPTALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed