Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | DDO | Q99489 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743608 | 0.83 | RXFP1 (0.53) | RXFP1KDM4EALDH1A1GLAHSD17B10 | |
| SCHEMBL4746968 | 0.82 | RXFP1 (0.63) | RXFP1KDM4EALDH1A1GLAHSD17B10 | |
| SCHEMBL4745410 | 0.82 | RXFP1 (0.69) | RXFP1KDM4EALDH1A1GLAHSD17B10 | |
| SCHEMBL4746065 | 0.80 | RXFP1 (0.57) | RXFP1KDM4EALDH1A1GLAHSD17B10 | |
| SCHEMBL14068807 | 0.79 | ALDH1A1 (0.54) | KDM4EALDH1A1GLAHSD17B10SMN1; SMN2 | |
| SCHEMBL4072838 | 0.74 | KDM4E (0.61) | RXFP1KDM4EALDH1A1GLAHSD17B10 | |
| SCHEMBL13436118 | 0.71 | SCN8A (0.54) | KDM4EALDH1A1SCN8ANPSR1ATM | |
| SCHEMBL5460835 | 0.71 | KDM4E (0.57) | RXFP1KDM4EALDH1A1GLAHSD17B10 | |
| SCHEMBL17505178 | 0.70 | KDM4E (0.61) | RXFP1KDM4EALDH1A1GLAHSD17B10 | |
| SCHEMBL12559601 | 0.67 | DAO (0.71) | RXFP1KDM4EALDH1A1GLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113006-A1 | METHODS OF USING QUINOLINONE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008113006-A1 | METHODS OF USING QUINOLINONE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-18 | — | — | WO | disclosed |