Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylphenylether SCHEMBL27363693 | 0.88 | ALDH1A1 (0.61) | LTA4HEPHX2FFAR1LMNACYP1A2 | |
| SCHEMBL18429764 | 0.87 | LMNA (0.59) | LTA4HEPHX2LMNACYP1A2PTGS1 | |
| SCHEMBL29045776 | 0.87 | LMNA (0.59) | LTA4HEPHX2LMNACYP1A2PTGS1 | |
| SCHEMBL10795544 | 0.85 | FOXM1 (0.57) | LTA4HEPHX2FFAR1FFAR4LMNA | |
| SCHEMBL5700 | 0.84 | LTA4H (0.80) | LTA4HEPHX2FFAR1FFAR4LMNA | |
| Di(Hydroxyethyl)Ether SCHEMBL16085977 | 0.84 | TDP1 (0.58) | LTA4HEPHX2FFAR1 | |
| SCHEMBL1180141 | 0.84 | TDP1 (0.58) | LTA4HEPHX2FFAR1 | |
| SCHEMBL3589930 | 0.83 | FFAR1 (0.75) | LTA4HEPHX2FFAR1FFAR4 | |
| SCHEMBL9451327 | 0.83 | ALDH1A1 (0.69) | LTA4HEPHX2LMNACYP1A2PTGS1 | |
| SCHEMBL4884524 | 0.83 | LTA4H (0.58) | LTA4HEPHX2FFAR1FFAR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |