Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743996 | 0.84 | CA1 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL21670744 | 0.82 | GLA (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14068323 | 0.81 | CYP1A2 (0.45) | KDM4ECHRM2CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL2356251 | 0.80 | LMNA (0.47) | KDM4ECHRM2CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL5591066 | 0.79 | BCHE (0.47) | KDM4EBCHEACHEPTGS2S1PR1 | |
| SCHEMBL6228744 | 0.75 | ACHE (0.42) | KDM4EBCHEACHEPTGS2CYP2D6 | |
| SCHEMBL21670745 | 0.75 | TSHR (0.50) | BCHEACHEPTGS2SMN1; SMN2LMNA | |
| SCHEMBL28805745 | 0.74 | CHRM2 (0.66) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14739541 | 0.73 | CHRM2 (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8345386 | 0.73 | L3MBTL1 (0.41) | HDAC1KDM4ECHRM2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |