Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228744 | 0.80 | ACHE (0.42) | L3MBTL1MEN1KMT2AMAPK1BCHE | |
| SCHEMBL10054980 | 0.80 | SIGMAR1 (0.50) | MEN1KMT2ASIGMAR1TDP1OPRM1 | |
| SCHEMBL14068323 | 0.78 | CYP1A2 (0.45) | L3MBTL1KDM4ETHRBTDP1CYP1A2 | |
| SCHEMBL2356251 | 0.77 | LMNA (0.47) | L3MBTL1KDM4ETHRBTDP1CYP1A2 | |
| SCHEMBL2047868 | 0.75 | ACHE (0.44) | L3MBTL1MEN1KMT2ABCHEACHE | |
| SCHEMBL2046392 | 0.75 | HRH3 (0.48) | ALDH1A1BCHEACHEPTGS2HRH3 | |
| SCHEMBL3037243 | 0.75 | TAAR1 (0.57) | SIGMAR1OPRM1OPRK1CYP1A2CYP2D6 | |
| SCHEMBL6203608 | 0.75 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1BCHEACHE | |
| SCHEMBL4743388 | 0.73 | HDAC3 (0.45) | MAPK1BCHEACHEPTGS2KDM4E | |
| SCHEMBL14739541 | 0.73 | CHRM2 (0.42) | L3MBTL1KDM4ETHRBTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009602-A1 | PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |