Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743411 | 0.86 | ALDH1A1 (0.51) | MEN1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL14024992 | 0.77 | RAB9A (0.63) | RAB9ANPC1HTTMEN1TP53 | |
| SCHEMBL8283845 | 0.77 | ALDH1A1 (0.62) | MEN1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL4747138 | 0.76 | CHRM2 (0.63) | MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL4744580 | 0.75 | RAB9A (0.77) | RAB9ANPC1HTTMEN1TP53 | |
| SCHEMBL2831462 | 0.74 | NPC1 (0.77) | RAB9ANPC1HTTMEN1TP53 | |
| SCHEMBL1474021 | 0.74 | ALDH1A1 (0.65) | RAB9ANPC1HTTMEN1HPGD | |
| SCHEMBL13720058 | 0.73 | NPC1 (1.00) | RAB9ANPC1HTTMEN1TP53 | |
| SCHEMBL11616834 | 0.73 | HTT (1.00) | RAB9ANPC1HTTMEN1TP53 | |
| SCHEMBL4787428 | 0.73 | ROCK2 (0.64) | RAB9ANPC1HTTMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |