Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743532 | 0.84 | GFER (0.70) | ALDH1A1HTTNPSR1GFERCA1 | |
| SCHEMBL4743949 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HTTNPSR1GFERCA1 | |
| SCHEMBL4743510 | 0.82 | TUBB4A (0.63) | ALDH1A1HTTNPSR1GFERCA1 | |
| SCHEMBL4743525 | 0.81 | CA1 (0.56) | ALDH1A1HTTNPSR1GFERCA1 | |
| SCHEMBL4746720 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HTTNPSR1GFERCA1 | |
| SCHEMBL4746660 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HTTNPSR1GFERCA1 | |
| SCHEMBL4747296 | 0.79 | KMT2A (0.54) | ALDH1A1HTTNPSR1GFERCA1 | |
| SCHEMBL4743966 | 0.79 | CA1 (0.53) | ALDH1A1HTTNPSR1GFERCA1 | |
| SCHEMBL4744282 | 0.79 | TUBB4A (0.55) | ALDH1A1HTTNPSR1GFERCA1 | |
| SCHEMBL4748024 | 0.79 | CA1 (0.67) | ALDH1A1HTTNPSR1GFERCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |