Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352344 | 0.92 | ALDH1A1 (0.80) | ALDH1A1NPSR1MAPTPKMSMN1; SMN2 | |
| SCHEMBL7973719 | 0.89 | ALDH1A1 (0.85) | ALDH1A1NPSR1MAPTPKMSMN1; SMN2 | |
| SCHEMBL11048929 | 0.85 | MAPT (0.65) | ALDH1A1NPSR1MAPTPKMSMN1; SMN2 | |
| SCHEMBL17678158 | 0.84 | SMN1; SMN2 (0.57) | ALDH1A1NPSR1MAPTPKMSMN1; SMN2 | |
| SCHEMBL7767318 | 0.82 | MAPT (0.62) | ALDH1A1NPSR1MAPTPKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9760520 | 0.82 | SMN1; SMN2 (0.55) | ALDH1A1NPSR1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1520169 | 0.81 | MAPT (0.64) | ALDH1A1NPSR1MAPTPKMSMN1; SMN2 | |
| SCHEMBL741469 | 0.81 | MAPT (0.70) | ALDH1A1NPSR1MAPTPKMSMN1; SMN2 | |
| SCHEMBL17749591 | 0.81 | MAPT (0.61) | ALDH1A1NPSR1MAPTPKMSMN1; SMN2 | |
| SCHEMBL7973853 | 0.80 | KAT2B (0.66) | ALDH1A1NPSR1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |