Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALPG | P10696 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767318 | 0.94 | MAPT (0.62) | MAPTPKMLMNASMN1; SMN2TDP1 | |
| SCHEMBL741469 | 0.85 | MAPT (0.70) | MAPTPKMLMNASMN1; SMN2TDP1 | |
| SCHEMBL4743774 | 0.85 | ALDH1A1 (0.67) | MAPTPKMLMNASMN1; SMN2TDP1 | |
| SCHEMBL2016758 | 0.84 | MAPT (0.63) | MAPTPKMLMNASMN1; SMN2TDP1 | |
| SCHEMBL4980984 | 0.82 | HCAR3 (0.58) | MAPTPKMLMNASMN1; SMN2TDP1 | |
| SCHEMBL1283854 | 0.82 | MAPT (0.54) | MAPTPKMLMNASMN1; SMN2TDP1 | |
| SCHEMBL1520169 | 0.82 | MAPT (0.64) | MAPTPKMLMNASMN1; SMN2TDP1 | |
| SCHEMBL17749591 | 0.82 | MAPT (0.61) | MAPTPKMLMNASMN1; SMN2TDP1 | |
| SCHEMBL5309199 | 0.82 | MAPT (0.66) | MAPTPKMLMNASMN1; SMN2TDP1 | |
| SCHEMBL5352344 | 0.81 | ALDH1A1 (0.80) | MAPTPKMLMNASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432769-A | MADE BY REACTING 3-AMINO-4-NITRO-CHLOROBENZENE WITH GLYCEROL | L'OREAL (FR) | 1984-02-21 | — | — | US | disclosed |