Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | ALPG | P10696 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313477 | 0.85 | KAT2B (0.69) | MAPTLMNASMN1; SMN2ALPGTDP1 | |
| SCHEMBL739095 | 0.85 | MAPT (0.64) | MAPTLMNASMN1; SMN2ALPGTDP1 | |
| SCHEMBL11048929 | 0.85 | MAPT (0.65) | MAPTLMNASMN1; SMN2ALPGTDP1 | |
| SCHEMBL7745956 | 0.84 | LMNA (0.57) | MAPTLMNASMN1; SMN2ALPGTDP1 | |
| SCHEMBL6474886 | 0.84 | LMNA (0.57) | MAPTLMNASMN1; SMN2ALPGTDP1 | |
| SCHEMBL1046670 | 0.84 | LMNA (0.57) | MAPTLMNASMN1; SMN2ALPGTDP1 | |
| SCHEMBL7767318 | 0.82 | MAPT (0.62) | MAPTLMNASMN1; SMN2ALPGTDP1 | |
| SCHEMBL12555416 | 0.82 | MAPT (1.00) | MAPTLMNASMN1; SMN2ALPGTDP1 | |
| SCHEMBL4743774 | 0.81 | ALDH1A1 (0.67) | MAPTLMNASMN1; SMN2ALPGTDP1 | |
| SCHEMBL2220740 | 0.81 | MAPT (0.59) | MAPTLMNASMN1; SMN2ALPGTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |